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    4 repositories

    • Gottwein_CRISPR_Variant_Calling

      Public
      Script for characterizing and quantiftying variants based on data returned from the Massachusetts General Hospital CCIB DNA Core.
      Python
      •
      MIT License
      •0•0•0•0•Updated Aug 15, 2022Aug 15, 2022

    • 2022_cFLIP_Stats_Figures

      Public
      Code and workbooks for figures and statistical testing from 2022 manuscript in preparation.
      Jupyter Notebook
      •
      MIT License
      •0•0•0•0•Updated Aug 15, 2022Aug 15, 2022

    • DepMap_Mining

      Public
      Code for identifying cohort-specific oncogenic dependencies and cohort-insensitive pan-essentials using DepMap + a cohort of CRISPR screens analyzed with MAGeCk.
      Jupyter Notebook
      •
      MIT License
      •2•1•0•0•Updated Mar 14, 2022Mar 14, 2022

    • CRISPR_Screen_Processing

      Public
      A basic working example that you can follow through to semi-automate the analysis of pooled CRISPR screen data in a uniform way using MAGeCK and/or DrugZ for enrichment/depletion analysis. See ReadMe for more details. Testing table files are templates, not working examples.
      Shell
      •
      MIT License
      •1•0•0•0•Updated Mar 10, 2021Mar 10, 2021