Minor tweaks to improve flow and clarity #278
Conversation
| biological principles of inheritance, DNA duplication, and recombination; they can be | ||
| created by [evolutionary simulation](https://tskit.dev/software/#simulate) or by | ||
| [inferring genealogies from empirical DNA data](https://tskit.dev/software/#infer). | ||
| biological principles of inheritance, DNA duplication, mutation, and recombination; |
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Just to make it clear that mutation is also important.
| @@ -85,8 +85,9 @@ Tree sequences are used to encode and analyse large genetic datasets | |||
| Tree sequences provide an efficient way of storing | |||
| [genetic variation](https://en.wikipedia.org/wiki/Genetic_variation) data, and can | |||
| power analyses of millions of whole [genomes](https://en.wikipedia.org/wiki/Genome). | |||
| Plots (a) and (b) summarize results presented | |||
| [further](plot_storing_everyone) [down](plot_incremental_calculation) this tutorial. | |||
| Plots (a) and (b) below summarize these aspects | |||
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I found this bit to now flow well.
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Thanks, all LGTM. I'll wait for @hyanwong to merge as I think he wrote the original |
| position on the chromosome. We can mark these extra "ancestral genomes" on our tree | ||
| diagrams, distinguishing them from the *sampled* genomes ($\mathrm{a}$ to $\mathrm{j}$) | ||
| by using circular symbols. We can even colour the nodes by the population that we know | ||
| which is a MRCA of the descendant genomes at that position on the chromosome. |
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We don't define MRCA anywhere previously, do we? So I think we do need to spell it out here.
| @@ -187,8 +195,8 @@ In fact, succinct tree sequences don't store each tree separately, but instead a | |||
| based on an interconnected *genetic genealogy*, in which | |||
| [genetic recombination](https://en.wikipedia.org/wiki/Genetic_recombination) has led | |||
| to different regions of the chromosome having different histories. Another way of | |||
| thinking about the tree sequence above is that it describes the full genetic | |||
| *family "tree"* (strictly, "network") of our 10 genomes. | |||
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I think it's helpful to mention "network" somewhere, as that's in the title. I also think a "genetic family tree" is worth mentioning somewhere, but perhaps not here. I'm happy to merge this and add something like this sentence in again at the top.
I don't think I have permissions to merge on this repo @benjeffery. Perhaps I should have? |
Invite sent! |
I read the
what_is.mdthe other day and thought these edits would improve flow and add clarity for those that lack some training in tree-stuff. Take what you find useful.