Genomic Data Management and Analysis

This miniproject is part of 'Fundamentals of Python Programming' virtual internship conducted by Nyberman Bioinformatics, Europe. This project involves data sorting & extraction, data analysis, and data visualization. I have used the Python programming language and Spyder IDE for the analysis and visualization of data. The dataset consists of protein sequences in fasta format, along with other files such as .vcf and .txt files containing sequence information.

Data Sorting & Extraction:

• Search for fasta files within specified directories and copy them to a new location. This involves identifying fasta files, moving them to a designated folder
• Extract the first line from each fasta file and record it in a text file. This involves reading each fasta file, extracting the first line, and associating it with the corresponding sample name

Data Analysis:

• Generate details of each folder in a summary CSV file, including the number of files and the list of files present in each folder. This involves traversing through directories, counting files, and compiling a summary report
• Identify the vcf file, read it into a tabular format
• Filter for variants in chromosome 21

Data Visualization:

• Create a bar chart showing the count of variants on each chromosome. Each chromosome can be represented by a bar, with the height of the bar indicating the total count of variants on that chromosome

Click here to view python script and complete analysis of the project

Count of variants on each chromosome

First line from each fasta file

Summary of all files present in each folder