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Additional Fields
Mathew Thorpe edited this page Apr 13, 2022
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Variable / Field Name | Description | Field Type | Field Label | Choices or Calculations |
---|---|---|---|---|
tier | Patient tier, defined by a 3 or 12 month visit | numeric | !is.na(crf3b_visit) = 2 ; is.na(crf3b_visit) = 1 | |
age_admission_factor | Age grouped into factors | factor | Age at admission (y) | <30 ; 30-39 ; 40-49 ; 50-59 ; 60-69 ; 70-79 |
crf1b_eth_5levels | Ethnicity grouped into character factors | factor | Ethnicity | White ; Black ; Other ; South Asian ; Mixed |
crf1b_eth_pft | Ethnicity grouped into numeric factors | factor | Ethnicity | 1, White ; 2, Black ; 3, Other ; 4,South Asian ; 5, Mixed |
crf1a_com_mer_diab_yn | Diabetes yes/no | yesno | Diabetes | if_else(crf1a_com_mer_diab == "Type 1" |
crf1a_com_mh_stm_yn | Malignancy yes/no | yesno | Malignancy | if_else(crf1a_com_mh_stm == "Localised" |
no_comorbid | Number of comorbidities | numeric | Number of comorbidities | Sums "yes" for the following variables: crf1a_com_mer_diab_yn, crf1a_com_card_mi, crf1a_com_mh_stm_yn, crf1a_com_card_ihd, crf1a_com_card_af, crf1a_com_card_ht, crf1a_com_card_chf, crf1a_com_card_chd, crf1a_com_card_vhd, crf1a_com_card_pid, crf1a_com_card_pvd, crf1a_com_card_hcd, crf1a_com_neuspy_dem, crf1a_com_neuspy_da, crf1a_com_neuspy_chron, crf1a_com_neuspy_pam, crf1a_com_neuspy_ptm, crf1a_com_res_copd, crf1a_com_res_ast, crf1a_com_res_ild_yn, crf1a_com_res_bron, crf1a_com_res_osa, crf1a_com_res_ohs, crf1a_com_res_pe, crf1a_com_rheu_ctd, crf1a_com_rheu_ra, crf1a_com_rheu_ost, crf1a_com_gast_pud, crf1a_com_gast_gord, crf1a_com_gast_ibd, crf1a_com_gast_ibs, crf1a_com_mer_hypot, crf1a_com_mer_hypert, crf1a_com_mer_ckd_yn, crf1a_com_leuk_yn, crf1a_com_lymp_yn, crf1a_com_id_aids, crf1a_com_id_hiv, crf1a_com_id_other_yn |
no_comorbid_3levels | Number of comorbidies, grouped into three character factors | factor | Number of comorbidities (factor) | Sum threshold from no_comorbid - No comorbidity ; 1 comorbidity ; 2+ comorbidity |
no_comorbid_2levels | Number of comorbidies, grouped into two character factors | factor | Number of comorbidities (factor) | Sum threshold from no_comorbid - No comorbidity ; 1 comorbidity |
crf1a_symptom_duration | Duration of symptoms in days, from date of first symptom onset to date of admission to hospital | numeric | Symptom duration (days) | crf1a_date_adm - crf1a_date_first_symptoms |
crf1a_admission_duration | Duration of admission in days, from date of admission to date of discharge from hospital | numeric | Admission duration (days) | crf1a_date_dis - crf1a_date_adm |
crf1a_com_card | Summary variable for cardiovascular comorbidities | yesno | Cardiovascular | "Yes" if any variable starting with "crf1a_com_card" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_res | Summary variable for respiratory comorbidities | yesno | Respiratory | "Yes" if any variable starting with "crf1a_com_res" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_gast | Summary variable for gastrointestinal comorbidities | yesno | Gastrointestinal | "Yes" if any variable starting with "crf1a_com_gast" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_neupsy | Summary variable for neurological and psychiatric comorbidities | yesno | Neurological and psychiatric | "Yes" if any variable starting with "crf1a_com_neupsy" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_rheu | Summary variable for rheumatological comorbidities | yesno | Rheumatological | "Yes" if any variable starting with "crf1a_com_rheu" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_mer | Summary variable for metabolic/endocrine/renal comorbidities | yesno | Metabolic/endocrine/renal | "Yes" if any variable starting with "crf1a_com_mer" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_mh | Summary variable for malignancy comorbidities | yesno | Malignancy | "Yes" if any variable starting with "crf1a_com_mh" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_id | Summary variable for infectious disease comorbidities | yesno | Infectious disease | "Yes" if any variable starting with "crf1a_com_id" and NOT containing "other" is "Yes", otherwise "No" |
crf1a_com_diab | Special diabetes variable - only includes Type 2 (Type 1 set to 'No') | factor | Diabetes | Takes crf1a_com_mer_diab, recodes "Type 1" as "No", keeps only "Type 2" |
crf3a_bmi | BMI variable, taken from CRF3a resting weight/height | numeric | BMI | (crf3a_rest_weight / (crf3a_rest_height / 100)^2) |
crf3a_bmi_5levels | BMI, grouped into five character factors | factor | BMI (5 levels) | Underweight (<18.5) ; Normal weight (18.5 to 24.9) ; Overweight (25 to 29.9) ; Obese (30 to 39.9) |
crf3a_bmi_2levels | BMI, grouped into two character factors | factor | BMI (2 levels) | BMI < 30 kg/m^2 ; BMI 30+ kg/m^2 |
eq5d5l_summary_delta | Difference in self-reported health pre vs post hospitalisation | numeric | How good or bad is your health overall? 3 months vs pre-covid | eq5d5l_summary - eq5d5l_summary_pre |
eq5d5l_summary_delta_change | Difference in self-reported health pre vs post hospitalisation, grouped into three character factors | factor | No change ; Improvement ; Worse | |
eq5d5l_total_pre | EQ5D sum across domains pre hospitalisation | numeric | EQ5D sum of domains pre-covid | sum(eq5d5l_q1_pre:eq5d5l_q5_pre) |
eq5d5l_total | EQ5D sum across domains post hospitalisation | numeric | EQ5D sum of domains | sum(eq5d5l_q1:eq5d5l_q5) |
eq5d5l_total_delta | EQ5D change in sum of domains | factor | EQ5D change in sum of domains | No change ; Improvement ; Worse |
eq5d5l_q_numeric | EQ5D numeric post covid | numeric | as.numeric(eq5d5l_q1:eq5d5l_q5) | |
eq5d5l_q_pre_numeric | EQ5D numeric pre covid | numeric | as.numeric(eq5d5l_q1_pre:eq5d5l_q5_pre) | |
eq5d5l_q_delta | EQ5D change | numeric | eq5d5l_q_numeric - eq5d5l__q_pre_numeric | |
eq5d5l_q_delta_change | EQ5D change, grouped into three character factors | factor | No change ; Improvement ; Worse | |
eq5d_population_norm | EQSD population norms | numeric | age_admission < 25 = 0.940 ; age_admission < 35 = 0.927 ; age_admission < 45 = 0.911 ; age_admission < 55 = 0.847 ; age_admission < 65 = 0.799 ; age_admission < 75 = 0.779 | |
eq5d5l_utility_index_pre | EQSD utility index pre covid | numeric | ||
eq5d5l_utility_index | EQSD utility index post covid | numeric | ||
eq5d5l_utility_index_delta | EQSD utility index change | numeric | EQ5D utility index (difference) | |
patient_sq_l_*_numeric | Numeric versions of columns starting with patient_sq_l_ | numeric | ||
patient_sq_l_t_seeing_delta | Change in difficulty seeing, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_hearing_delta | Change in difficulty hearing, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_walking_delta | Change in difficulty walking, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_remembering_delta | Change in difficulty remembering, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_self_care_delta | Change in difficulty taking care of yourself, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_communicate_delta | Change in difficulty communicating, from precovid to today, in numeric format | numeric | ||
patient_sq_l_t_seeing_delta_change | Change in difficulty seeing, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_hearing_delta_change | Change in difficulty hearing, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_walking_delta_change | Change in difficulty walking, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_remembering_delta_change | Change in difficulty remembering, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_self_care_delta_change | Change in difficulty taking care of yourself, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_communicate_delta_change | Change in difficulty communicating, from precovid to today, grouped into three character factors | Factor | No change ; Improvement ; Worse | |
patient_sq_l_t_disability | Summary variable for those with a disability (any of the above patient_sq_l_t variables) | Factor | WG-SS: any 'Yes - lot of difficulty' | "Yes" if any variable starting with "patient_sq_l_t_" is "Yes", otherwise "No" |
patient_sq_l_t__new_disability | Summary variable for those with a new disability, derived from patient_sq_l_t_*_delta variables | Factor | WG-SS: new disability | "Yes" ; "No" (see 03_prep.R for detailed calculation) |
psq_scale_blness_delta | Change in breathlessness, within 24h - precovid | numeric | ||
psq_scale_fatigue_delta | Change in fatigue, within 24h - precovid | numeric | ||
psq_scale_cough_delta | Change in cough, within 24h - precovid | numeric | ||
psq_scale_pain_delta | Change in pain, within 24h - precovid | numeric | ||
psq_scale_sleep_delta | Change in sleep quality, within 24h - precovid | numeric | ||
psq_scale_blness_delta _change | Change in sleep quality, within 24h - precovid, grouped into three character factors | factor | No change ; Improvement ; Worse | |
psq_scale_fatigue_delta _change | Change in sleep quality, within 24h - precovid, grouped into three character factors | factor | No change ; Improvement ; Worse | |
psq_scale_cough_delta _change | Change in sleep quality, within 24h - precovid, grouped into three character factors | factor | No change ; Improvement ; Worse | |
psq_scale_pain_delta _change | Change in sleep quality, within 24h - precovid, grouped into three character factors | factor | No change ; Improvement ; Worse | |
psq_scale_sleep_delta _change | Change in sleep quality, within 24h - precovid, grouped into three character factors | factor | No change ; Improvement ; Worse | |
gad7_summary_2levels | GAD7, grouped into two character factors | factor | Anxiety (GAD7 >8) | "Yes" ; "No" |
phq9_summary_2levels | PHQ9, grouped into two character factors | factor | Depression (PHQ-9 >= 10) | "Yes" ; "No" |
pcl5_summary_2levels | PCL5, grouped into two character factors | factor | PTSD (PCL-5 >= 38) | "Yes" ; "No" |
dyspnoea12_summary | Summary variable for those with dyspnoea | numeric | Dyspnoea-12 score | Sum all columns starting with "dysp" |
bpi_severity_summary | Summary variable for those with BPI | numeric | BPI severity | Sum all columns between "bpi_worst" and "bpi_rightnow" |
bpi_interference_summary | Summary variable for those with BPI interference | numeric | BPI interference | Sum all columns between "bpi_past24_general" and "bpi_past24_enjoyment" |
sppb_score_summary | SPPB, grouped into two character factors | factor | SPPB (mobility disability <=10 | "Yes" ; "No" |
rcf_score_numeric | Rockwood clinical frailty score, as numeric | numeric | RCF score (numeric) | as.numeric(rcf_score) |
rcf_score_summary | Rockwood clinical frailty score, grouped into two character factors | factor | Rockwood clinical frailty score >=5 | "Yes" ; "No" |
mocal_total_summary | Summary MOCA variable | factor | MOCA <23 | If < 23 then "Yes" ; If >= 23 then "No" |
crf1a_resp_support_8levels | Respiratory support variable, grouped into eight character factors | factor | Maximal organ support | "ECMO" ; "RRT" ; "IMV" ; "HFN" ; "BIPAP" ; "CPAP" ; "O2" ; "No respiratory support" |
crf1a_resp_support_4levels | Respiratory support variable, grouped into four character factors according to the WHO clinical progression scale | factor | WHO clinical progression scale | "WHO – class 3-4" ; "WHO – class 5" ; "WHO – class 6" ; "WHO – class 7-9" |
mocal_total_corrected | MOCA adjusted for level of education attainment | numeric | If crf1b_edu == "None", "Primary School" or "Secondary School", mocal_total + 1 otherwise mocal_total | |
mocal_total_corrected_summary | Summary corrected MOCA variable | factor | MOCA (corrected) <23 | "Yes" ; "No" |
bnp_summary | Summary variable for BNP/NT-Pro_BNP over threshold | factor | BNP/NT-Pro-BNP above threshold | "Yes" ; "No" |
hba1c_summary | Summary variable for HbA1c greater than 6.0 | factor | HbA1C above threshold (>=6.0%) | "Yes" ; "No" |
egfr_summary | Summary variable for eGFR greater than 60 | factor | eGFR < 60 ml/min/1.73 m2 | "Yes" ; "No" |
ddi_summary | Summary variable for D-dimer greater than 500 | factor | D-dimer (>= 500 ng/ml) | "Yes" ; "No" |
crp_summary | Summary variable for CRP greater than 10 | factor | CRP (>10 mg/L) | "Yes" ; "No" |
social_status_after | Variable to evaluate if occupation/working status has changed since COVID | factor | Occupation/working status since COVID-19 | If patient_sq_q == "Same as before" then social_status_before, if patient_sq_q == "Different from before" and social_status_before != patient_sq_q_today then patient_sq_q_today |
working_status_change | Variable to evaluate if occupation/working status has changed | factor | If patient_sq_q == "Different from before" then "Yes" ; if patient_sq_q == "Same as before" then "No" | |
working_less | Variable to evaluate if patient is working less | factor | If working_status_change == "Yes" AND social_status_before == "Working full-time" AND patient_sq_q_today == "Working part-time" THEN "Yes" ; If working_status_change == "Yes" OR working_status_change == "No" THEN "No" | |
working_before | Variable to evaluate if patient was working before COVID | factor | If social_status_before == "Working full-time" OR "Working part-time" THEN "Yes", otherwise "No" | |
no_longer_working | Variable to evaluate if patient is no longer working | factor | If working_status_change == "Yes" AND patient_sq_q_today == "Full time carer (children or other)" OR "Unemployed" OR "Unable to work due to chronic illness" OR "Student" OR "Retired" OR "Medically retired" OR "Prefer not to say" then "Yes", otherwise "No" | |
health_reasons | Variable to evaluate if patient has an altered working status due to health reasons | factor | If patient_sq_q_change == "Poor health" OR "Sick leave" THEN "Yes", otherwise "No" | |
employer_reasons | Variable to evaluate if patient has an altered working status due to employer reasons | factor | If patient_sq_q_change == "Made redundant" OR "Working hours reduced by employer" THEN "Yes", otherwise "No" | |
other_reasons | Variable to evaluate if patient has an altered working status due to other reasons | factor | If patient_sq_q_change == "New caring responsibility" OR "Other" OR "Prefer not to say" THEN "Yes", otherwise "No" | |
pft_fev1 | Mean of PFT FEV1 readings | numeric | FEV1 | If variable starts with "pft_fev1_r" then calculate mean between variables |
pft_fvc | Mean of PFT FVC readings | numeric | FVC | If variable starts with "pft_fvc_r" then calculate mean between variables |
pft_fev1_fvc | Ratio FEV1:FVC | numeric | FEV1/FVC | pft_fev1 / pft_fvc |
pft_tlco | Mean of PFT TLCO readings | numeric | TLCO | If variable starts with "pft_tlco_r" then calculate mean between variables |
pft_kco | Mean of PFT KCO readings | numeric | KCO | If variable starts with "pft_kco_r" then calculate mean between variables |
pft_mip | Mean of PFT MIP readings | numeric | MIP | If variable starts with "pft_mip_r" then calculate mean between variables |
pft_mep | Mean of PFT MEP readings | numeric | MEP | If variable starts with "pft_mep_r" then calculate mean between variables |
pft_fev1_pred | Prediction of FEV1 readings using GLI equations | numeric | pred_GLI(age_admission, crf3a_rest_height / 100, crf1a_sex, crf1b_eth_pft, param = c("FEV1")) | |
pft_fvc_pred | Prediction of FVC readings using GLI equations | numeric | pred_GLI(age_admission, crf3a_rest_height / 100, crf1a_sex, crf1b_eth_pft, param = c("FVC")) | |
pft_fev1_perc_pred | Percentage of FEV1 predicted | numeric | FEV1 % predicted | 100 * pft_fev1 / pft_fev1_pred |
pft_fvc_perc_pred | Percentage of FVC predicted | numeric | FVC % predicted | 100 * pft_fvc / pft_fvc_pred |
pft_fev1_perc_pred_80 | Percentage of FEV1 predicted over 80% | numeric | FEV1 % pred <80% | If < 80 then "Yes" ; If >= 80 then "No" |
pft_fvc_perc_pred_80 | Percentage of FVC predicted over 80% | numeric | FVC % pred <80% | If < 80 then "Yes" ; If >= 80 then "No" |
pft_fev1_fvc_70 | Ratio FEV1:FVC less than 0.7 | numeric | FEV1/FVC <0.7 | If < 0.7 then "Yes" ; If >= 0.7 then "No" |
imd | Index of Multiple Deprivation (IMD) | numeric | See 03_prep.R for full calculation | |
imd_quintile | Index of Multiple Deprivation (IMD) quintile | factor | Index of multiple deprivation | See 03_prep.R for full calculation |
swab_pcr_result | COVID swab PCR test result | factor | SARS-CoV-2 swab | "Positive" ; "Indeterminate" ; "Negative" |
Contents
Case Report Form Definitions
- Forms
- Timepoints
- PHOSP ID
- eConsent Tier 1
- eConsent Tier 2
- Informed Consent Form
- Split Tier Consent
- Eligibility Checklist
- CRF1A Part 1
- CRF1A Part 2
- CRF1A Part 3
- CRF1B
- CRF2A
- CRF2B
- CRF3A
- CRF3B
- CRF3C
- CRF4A
- CRF4B
- CRF Emergency Visit
- Adverse Event Log
- Withdrawals
- CRF Early Termination
- CRF Tier 2 Withdrawal
- Medications Log
- Activity Monitor Log
- Mental Health Assessment
- Nutrition
- Social History
- EQ-5D-5L
- GAD-7
- PHQ-9
- MRC Dyspnoea
- SARC-F
- GPPAQ
- Dyspnoea-12
- FACIT Fatigue
- PCL-5
- BPI
- NEADL
- MoCA
- Rockwood Clinical Frailty
- PSQI
- MEQ
- LCQ
- PFTs
- Walk Tests
- Tier 2 Core Test Checklist
- Tier 2 Research Samples
- Tier 2 Notification - Blood
- Tier 2 Notification - Oral Wash
- Tier 2 Notification - Sputum
- Tier 2 Notification - Urine
- QRISK3
- BIA
- DXA
- Muscle Strength
- SPPB
- Pre-PSQ
- PSQ
- Lab Log - Routine Blood
- Lab Log - Urine
- Lab Log - Immuno
- Lab Log - Additional Tests
- PCR Swab Tests