Chaphamaparvovirus Extension Data

Background

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Chaphamaparvoviruses belong to the newly classified Hamaparvovirinae subfamily of the Parvoviridae family, with the genus name derived from the initial host groups: chiropteran (bats), avian (birds), and porcine (pigs). The genus includes 16 species, many of which have been recently discovered. Chaphamaparvoviruses appear to be widely distributed in vertebrate species, including rodents, birds, and reptiles.

Some viruses within this genus, such as mouse kidney parvovirus (MKPV), have been associated with significant health conditions in their hosts. MKPV, for example, was linked to inclusion body nephritis (IBN) in laboratory mice, resolving a long-standing mystery about this disease, which primarily affects immunodeficient mice.

Tilapia parvovirus (TiPV) has been implicated in mortality events among farmed tilapia, marking it as the first parvovirus confirmed to infect fish. Additionally, chaphamaparvoviruses have been detected in pigs (PPV7), dogs (Cachavirus), birds (e.g., turkey parvovirus 2), and vampire bats.

The diversity of chaphamaparvoviruses, as evidenced by their broad host range and frequent detection in metagenomic studies, underscores the potential importance of this genus in animal health and disease research across different species.

Reference Sequences

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Tabular data summarising chaphamaparvovirus species reference sequences can be found here.

Multiple Sequence Alignments

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Multiple sequence alignments (MSAs) spanning complete chaphamaparvovirus genomes can be found here.

Phylogenies

• Rep 78 tree

• VP1 tree

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