Tetraparvovirus Extension Data

Background

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Tetraparvoviruses are a genus within the Parvoviridae family, specifically part of the Parvovirinae subfamily, which encompasses viruses that infect vertebrates. They are distinguished from other parvoviruses by their unique genomic and host characteristics. Tetraparvoviruses are known for their ability to infect mammals, including humans and bats, though their clinical significance and epidemiological impact are still being explored.

Parvovirus 4 (PARV4) is a newly discovered human tetraparvovirus, first reported in 2005 in serum of intravenous drug users infected with hepatitis B virus. PARV4 infects a diverse range of hosts and has been classified into 3 genotypes; 1–3. Genotypes 1 and 2 occur more frequently in North America, Europe, and Asia, whereas genotype 3 is generaly found in sub-Saharan Africa.

Reference Sequences

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Tabular data summarising tetraparvovirus species reference sequences can be found here.

Multiple Sequence Alignments

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Multiple sequence alignments (MSAs) spanning complete tetraparvovirus genomes can be found here.

Phylogenies

• Rep 78 tree

• VP1 tree

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